Demystifying the endocannabinoid system. | Ruth Ross | TEDxMississauga
Dr. Ruth Ross describes what happens in the brain when introduced to tetrahydrocannabinol (THC), one of the primary ingredients in cannabis. This talk was …
Thanks for this clear breakdown of the ECS. Would love to hear the talk re: CBD that you said would be an entire other talk. The information out there is extremely confusing and limited re: how CBD actually interacts with our ECS. In turn, there is a lot of misinformation being shared everywhere by all kinds of publishers and companies.
Great presentation. Thank you. These are very insightful findings.
I'd like to see studies that compare medications/herbal interventions with lifestyle support changes that enhance the body's ability to self-sooth and self-regulate such as exercises or stimulating pressure points. Comparing it between no intervention and medication/herbal intervention doesn't give an accurate depiction of our choices.
If we discount the help our own body provides for us when given the opportunity, we set ourselves up for dependences and further complications.
Good concise talk. I am not pot user but strong supporter of decriminalization and appreciate good unbiased information… knowledge is power.
"The endocannabinoid system responds to singing and dancing." This makes me wonder about ancient cultures, Native Americans, and their harmony with plants and nature. Methinks humans need more connection to the plant world to live a happy and fulfilling life!
So it’s ok to take a pill to top up serotonin but not thc to up dopamine. Agenda.
I've never heard of anybody becoming a schizophrenic over getting too much THC! 🙄
Studies should be done on male vs female mental illness resulting from smoking pot during puberty.
why is that a plant like cannabis – hemp. has been so banned in so many states. its because it saves lives. it kills cancer and many other problems. we all have a endocannabinoid system in our bodies all the pollutant's in this world have brought this down to the point were people are getting cancer we all need to have it legalized in all 50 states. like jack herer said hemp – cannabis could save this world. my self I eat raw cannabis every day. it does not make me high but it helps with my epilepsy and my general health.
Well, Dont we have enough time by know to know it’s not harmfull in the long run? I thought it was. No death’s for at least 2000 thousand years. Thats not enough?
Lots of emotion and very little science in the commentary. The problem is the assumption or belief that an auto-regulating system (the endocannabinoid system is an auto regulating system that is part of a much larger auto regulating system called our entire body) can be used to fix problems. It can only be used if it is out of balance and the thing(s) you add specifically put it back into balance – otherwise you make the imbalance worse. It requires precision because counter-regulation means not enough or too much of something even if it is the right thing is as bad as or worse than the wrong thing. This system tells our brain where to make connections when it is developing and that happens a lot before we are born, for our first 5 years,and during puberty and out into our 20s. If you mess up the chemical balance or signalling connections end up malfunctioning or in the wrong places. These wiring problems are the genesis of mental health problems including schizophrenia. We know physical and mental stresses increase risks because they upset the balance. THC upsets the balance because it can't act like our own cannabinoid signallers because it can do different things at the same switch, sticks to it too long and sticks around too long (our own cannabinoids are "on demand") and gets in the way of our own signals trying to regulate themselves. The Big Pharma is a straw man argument. Our human physiology is designed to survive but it is imperfect. Illness is an imbalance of a signalling system because when signalling works it fixes itself. If we are going to take over that job with cannabinoids, or any other chemical regardless of its source, we need to understand it a lot better than we do, and recognize just because something affects a system doesn't mean it is always good. There is also plenty of evidence of harm. Even those who choose not to believe it cannot show evidence of safety because it has not been systematically measured in the broad population. It doesn't mean we can't find a way to use things that work on this system effectively and safely but we are still far from that understanding and design and testing of any manipulation of the cannabinoid system. This basic understanding of pharmacology started thousands of years ago with systematic assessments and measurement and refinement and purification and isolation og the ingredient that was the key to the balance. What is happening with cannabis is a dangerous shortcut with our population as the phase one study.
We don’t know if it’s safe? What do opioids do to you system and brain? Grade D- You get some credit for trying. Nothing new in the talk. Good luck big pharma!
This video reminds me that a medical dispensary recently opened less than 2 blocks from my house and I have no medical card and no buds… 🙁
What Dr. Ross said about it causing some psychosis made sense because there are people that can't handle it for sure. But juxtaposed against alcohol and opioids you can say cannabis is safe in my opinion. We are on the cusp of THC infused food and drink going legal in October 2019 so it will be interesting to see what happens. A lot of people simply can not inhale without coughing so bad they decide right there cannabis doesn't work. Be interesting to see what they say the first time they get stoned later this year. There should have been more about CBD and what role it plays hopefully the good doctor can do another Ted Talk.
But she would have dinner and a bottle of wine or a few beers without a second thought. Why is alcohol which has no medicinal value and is processed and causes illness and deaths be allowed but we are denied cannabis which saves lives? This is twisted. Money money money. Money matters more than lives. Money rules.
she know everything this pittfull human being trying her best to be liked! doctor this and that i represent Pharma dont say anything please! everything coming out sound like a sale trick for normal pharma!
Cbd oil helps me. That's all I care about.
Extremely weak talk. Clearly one-sided and myopic. Also, her pants fit horribly.
The random key analogy doesnt work.Cannabis/Hemp has been like the dog or horse in mankinds development,anyone who had a boat needed a rope,anyone who had a rope knew about Cannabis/hemp.
THC replaces anandamide and disturbs it's natural production. Anandamide seems rather important for managing mental illnesses. Which is why it makes Schizophrenia worse. Cannabidiol almost has opposite effect. And is all around a good guy molecule. Also exercising on THC is probably a good idea and easier than you might think. It would like having a runner's high before you run.
She told the story, the insight was good, she gave it a shot, it was ok!
Sounds like an agenda 🤔
Cannabis is ultimately harmful. Use at your own risk.
So what’s the alternative pharmacy drugs. I’ll stick with cannibus
With respect, so many years experience: We would of liked you to go into the effects of CBD on this system. "Too much THC makes you prang out and forgetful" yup. But.. What of the anti psychotic effects of CBD on the ECS? Why is it so insanely popular.. must be helping people or we wouldn't be forking out for it. Doesnt it regulate our ECS into homeostasis.. missed opportunity. Suspiciously one sided.
if we took her conclusion Big "R Little D (research & Development)" approach to transportation, automation or anything else we'd still be living in caves trying to light the fires with sticks! But hey, their type get paid to research and ponder, not to actually produce…
OI!!! HAVE YOU TRIED CANNABIS? DOCTOR? NO? shut up then
The powers-that-be always try to steer you away from thc, just like this talk. I'm not buying into her speech.
Typical doctor. Full of shite
The relationship between CBD and THC is FAR too important to just leave out. It's literally what protects your brain from THC's bad side and boosts it's medicinal properties. What a shame..
So many in society railing against the ills of cannabis use, so few against the uses of war…wonder which one is more dangerous…
She can say anything she wants. Someday if she is sitting in from of an Oncologist and they are telling her that the best plan of action is to fry her body with chemo and radiation and destroy her immune system, well she can refer back to this talk. My guess is, she is either a Big Pharma clone or she's backed by the FDA.
If it’s working, stop complaining and start celebrating. Seriously!
Wow, so disappointing to see a TedTalk with a guest that is giving BAD information. I have to wonder who is paying for her "research"….
As many of the popular comments under that video pointed out,
there are DEEP PROBLEMS, and DEEPER PROBLEMS, associated with respect to anyone actually 'employed' in established systems.
Generally speaking, people deliberately do NOT recognize their own surrounding keys and locks.
Is she forreal?? She is betting on the ignorance of humanity to fall for this… So, be afraid of weed… It could give you disease and other horrible stuff…. But, big pharma is turning weed into a prescription, so you be afraid of that cannabis, until pharmaceutical corporations can make billions off of their prescription version
Awesome lecture!! Love It!!
There is absolutely zero research that suggests THC can lead to schizophrenia.
The research shows many people with schizophrenia use THC to help them and often cure them completely.
This woman is too 'PC' and seems to be shilling a bit for big pharma.
I was tired and almost had a stroke reading the title at first glance
She needs to try cannabis before her next presentation.
B4 people in the cannabis community listen to people like this they first should ask:
1. who/what agency authorized this woman to study cannabis
2. Has this woman ever used cannabis before?
3. What is her agenda?
A major problem I gave is the use of the term medical cannabis. There is no such thing. It is a term that has been manufactured by the state and is a soft form of propaganda. The purpose being to disscredited the safety of non licensedl/home grown trees.
And then of course she said "WE" need to study it more. Why? Has it killed anyone? Since the answer is no, then she should have said that she WANTS to study it more. The way she left it is a tad too REEFER MADNESS 2019 for me.
Is this Sharon Osbourne??
Thanks for this clear breakdown of the ECS. Would love to hear the talk re: CBD that you said would be an entire other talk. The information out there is extremely confusing and limited re: how CBD actually interacts with our ECS. In turn, there is a lot of misinformation being shared everywhere by all kinds of publishers and companies.
Great presentation. Thank you. These are very insightful findings.
I'd like to see studies that compare medications/herbal interventions with lifestyle support changes that enhance the body's ability to self-sooth and self-regulate such as exercises or stimulating pressure points. Comparing it between no intervention and medication/herbal intervention doesn't give an accurate depiction of our choices.
If we discount the help our own body provides for us when given the opportunity, we set ourselves up for dependences and further complications.
Good concise talk. I am not pot user but strong supporter of decriminalization and appreciate good unbiased information… knowledge is power.
"The endocannabinoid system responds to singing and dancing." This makes me wonder about ancient cultures, Native Americans, and their harmony with plants and nature. Methinks humans need more connection to the plant world to live a happy and fulfilling life!
So it’s ok to take a pill to top up serotonin but not thc to up dopamine. Agenda.
I've never heard of anybody becoming a schizophrenic over getting too much THC! 🙄
Studies should be done on male vs female mental illness resulting from smoking pot during puberty.
why is that a plant like cannabis – hemp. has been so banned in so many states. its because it saves lives. it kills cancer and many other problems. we all have a endocannabinoid system in our bodies all the pollutant's in this world have brought this down to the point were people are getting cancer we all need to have it legalized in all 50 states. like jack herer said hemp – cannabis could save this world. my self I eat raw cannabis every day. it does not make me high but it helps with my epilepsy and my general health.
Well, Dont we have enough time by know to know it’s not harmfull in the long run? I thought it was. No death’s for at least 2000 thousand years. Thats not enough?
Lots of emotion and very little science in the commentary. The problem is the assumption or belief that an auto-regulating system (the endocannabinoid system is an auto regulating system that is part of a much larger auto regulating system called our entire body) can be used to fix problems. It can only be used if it is out of balance and the thing(s) you add specifically put it back into balance – otherwise you make the imbalance worse. It requires precision because counter-regulation means not enough or too much of something even if it is the right thing is as bad as or worse than the wrong thing. This system tells our brain where to make connections when it is developing and that happens a lot before we are born, for our first 5 years,and during puberty and out into our 20s. If you mess up the chemical balance or signalling connections end up malfunctioning or in the wrong places. These wiring problems are the genesis of mental health problems including schizophrenia. We know physical and mental stresses increase risks because they upset the balance. THC upsets the balance because it can't act like our own cannabinoid signallers because it can do different things at the same switch, sticks to it too long and sticks around too long (our own cannabinoids are "on demand") and gets in the way of our own signals trying to regulate themselves. The Big Pharma is a straw man argument. Our human physiology is designed to survive but it is imperfect. Illness is an imbalance of a signalling system because when signalling works it fixes itself. If we are going to take over that job with cannabinoids, or any other chemical regardless of its source, we need to understand it a lot better than we do, and recognize just because something affects a system doesn't mean it is always good.
There is also plenty of evidence of harm. Even those who choose not to believe it cannot show evidence of safety because it has not been systematically measured in the broad population. It doesn't mean we can't find a way to use things that work on this system effectively and safely but we are still far from that understanding and design and testing of any manipulation of the cannabinoid system. This basic understanding of pharmacology started thousands of years ago with systematic assessments and measurement and refinement and purification and isolation og the ingredient that was the key to the balance. What is happening with cannabis is a dangerous shortcut with our population as the phase one study.
We don’t know if it’s safe?
What do opioids do to you system and brain? Grade D-
You get some credit for trying.
Nothing new in the talk.
Good luck big pharma!
This video reminds me that a medical dispensary recently opened less than 2 blocks from my house and I have no medical card and no buds… 🙁
What Dr. Ross said about it causing some psychosis made sense because there are people that can't handle it for sure. But juxtaposed against alcohol and opioids you can say cannabis is safe in my opinion. We are on the cusp of THC infused food and drink going legal in October 2019 so it will be interesting to see what happens. A lot of people simply can not inhale without coughing so bad they decide right there cannabis doesn't work. Be interesting to see what they say the first time they get stoned later this year. There should have been more about CBD and what role it plays hopefully the good doctor can do another Ted Talk.
But she would have dinner and a bottle of wine or a few beers without a second thought. Why is alcohol which has no medicinal value and is processed and causes illness and deaths be allowed but we are denied cannabis which saves lives? This is twisted. Money money money. Money matters more than lives. Money rules.
she know everything this pittfull human being trying her best to be liked! doctor this and that i represent Pharma dont say anything please! everything coming out sound like a sale trick for normal pharma!
Cbd oil helps me. That's all I care about.
Extremely weak talk. Clearly one-sided and myopic. Also, her pants fit horribly.
The random key analogy doesnt work.Cannabis/Hemp has been like the dog or horse in mankinds development,anyone who had a boat needed a rope,anyone who had a rope knew about Cannabis/hemp.
THC replaces anandamide and disturbs it's natural production. Anandamide seems rather important for managing mental illnesses. Which is why it makes Schizophrenia worse. Cannabidiol almost has opposite effect. And is all around a good guy molecule.
Also exercising on THC is probably a good idea and easier than you might think. It would like having a runner's high before you run.
She told the story, the insight was good, she gave it a shot, it was ok!
Sounds like an agenda 🤔
Cannabis is ultimately harmful.
Use at your own risk.
So what’s the alternative pharmacy drugs. I’ll stick with cannibus
With respect, so many years experience:
We would of liked you to go into the effects of CBD on this system. "Too much THC makes you prang out and forgetful" yup.
But..
What of the anti psychotic effects of CBD on the ECS? Why is it so insanely popular.. must be helping people or we wouldn't be forking out for it.
Doesnt it regulate our ECS into homeostasis.. missed opportunity. Suspiciously one sided.
if we took her conclusion Big "R Little D (research & Development)" approach to transportation, automation or anything else we'd still be living in caves trying to light the fires with sticks! But hey, their type get paid to research and ponder, not to actually produce…
OI!!! HAVE YOU TRIED CANNABIS? DOCTOR? NO? shut up then
The powers-that-be always try to steer you away from thc, just like this talk. I'm not buying into her speech.
Typical doctor. Full of shite
The relationship between CBD and THC is FAR too important to just leave out. It's literally what protects your brain from THC's bad side and boosts it's medicinal properties. What a shame..
So many in society railing against the ills of cannabis use, so few against the uses of war…wonder which one is more dangerous…
She can say anything she wants. Someday if she is sitting in from of an Oncologist and they are telling her that the best plan of action is to fry her body with chemo and radiation and destroy her immune system, well she can refer back to this talk. My guess is, she is either a Big Pharma clone or she's backed by the FDA.
If it’s working, stop complaining and start celebrating. Seriously!
Wow, so disappointing to see a TedTalk with a guest that is giving BAD information. I have to wonder who is paying for her "research"….
As many of the popular comments under that video pointed out,
there are DEEP PROBLEMS, and DEEPER PROBLEMS, associated
with respect to anyone actually 'employed' in established systems.
Generally speaking, people deliberately do NOT
recognize their own surrounding keys and locks.
Is she forreal?? She is betting on the ignorance of humanity to fall for this… So, be afraid of weed… It could give you disease and other horrible stuff…. But, big pharma is turning weed into a prescription, so you be afraid of that cannabis, until pharmaceutical corporations can make billions off of their prescription version
Awesome lecture!! Love It!!
There is absolutely zero research that suggests THC can lead to schizophrenia.
The research shows many people with schizophrenia use THC to help them and often cure them completely.
This woman is too 'PC' and seems to be shilling a bit for big pharma.
I was tired and almost had a stroke reading the title at first glance
She needs to try cannabis before her next presentation.
B4 people in the cannabis community listen to people like this they first should ask:
1. who/what agency authorized this woman to study cannabis
2. Has this woman ever used cannabis before?
3. What is her agenda?
A major problem I gave is the use of the term medical cannabis. There is no such thing. It is a term that has been manufactured by the state and is a soft form of propaganda. The purpose being to disscredited the safety of non licensedl/home grown trees.
And then of course she said "WE" need to study it more. Why? Has it killed anyone? Since the answer is no, then she should have said that she WANTS to study it more. The way she left it is a tad too REEFER MADNESS 2019 for me.
Don't be duped fam.
she must had been stone during this presentation