"60 Minutes" report traces progression of Alzheimer's for 10 years
According to the Alzheimer’s Association, every 65 seconds someone in the United States develops the disease. For a remarkable report airing on “60 Minutes” …
this is so tragic. I wish for no one to experience a loved ones slow loss of their ability to remember speak or act themself
Sad 😢
My mom was diagnosed February 2018. By November 2018 she didn't recognize me, thought she lived somewhere else ( her former residence) and reported to Home Health in an Eval. that we were running a prostitution ring, sex trafficking ring with Dog the Bounty Hunter for a $250 registration fee.
I thought this was going to be a collage of 10 yrs. of the patient! 10years of seeing the disease progress, so we can get a better perspective. Too bad. Anyone know of a good link that provides this?
At least some risk factors are controllable: diabetes, obesity, high blood pressure, heart disease, head trauma, untreated sleep apnea (hypoxia) & overuse of benzodiazepines & other GABAergics like Ambien all increase your risk for dementia. Some cases are clearly genetic or sporadic but up to 1/3rd of cases could be prevented with healthy lifestyle changes according to studies. The role of high blood sugar/diabetes in dementia cannot be overstated. It damages the small vessels in the brain (microangiopathy), causing leaks that result in all kinds of problems.
For those of us who have dealt with loved ones with this disease, there will not be a toll for many of us, if we ourselves develop it. I, and many others, will take matters into our own hands once it's clear where this is going. This is not a reasonable quality of life.
I just recently left my 14 year career in long term care to start my own business, Reminisce Adult Day Services. I noticed the growing need for respite care for these caregivers. The toll it takes on their health and relationship is saddening. I provide care for their loved one on a regular basis so they can continue to live their lives and take care of their own health. I'm starting small in my local community but would love to expand and help spread this needed service. If you're curious visit http://www.reminisceadultdayservices.com or check us out on FB.
what a nightmare. continual heartbreaks that never let up … and when this woman dies, what is her poor husband supposed to do?
The importance of long-term care insurance cannot be stressed enough. It gives the spouse the ability to bring care into the home (and ultimately find a facility to their liking) and live with some measure of dignity and control in an incredibly difficult situation.
Well, Zaine, I will admit it WAS a major task to do what we did. We were lucky – no one ever dared to 'pounce' on us. One of the reasons: we had no money, (only enough to be refused Medicaid, which has a very low bar if you check the figure for eligibility). But we were praised as variously, "noble, inspired, compassionate, beyond amazing, dutiful, devoted.." on and on. All true. I am 70; my sister is in her late 60's. Mom died at home, in her bed, with us close by. She was 95 and had made her wishes very clear. However, the health care system in this country is a travesty, which caregivers often discover by painful investigation. We sure did!! That said – I would not have traded the experiences we had for anything in the world…but there are many gaps, Scandinavian countries put us to shame in their wonderful eldercare options..but caregivers must often also be warriors. And that, takes time away from the task we must attend to – looking after our beloved mother.We variously locked horns with her old employers, the health insurance company, a nursing home, her union, NYU Neurology, Medicaid, two corrupt eldercare lawyers, on and on…
Years ago, our mother was mis diagnosed, not once but TWICE with AD. What she actually had was mixed senile dementia. And, we then were refused help from Medicaid. That's the bad news. The good news: we had an enlightened Doctor, who suggested that we could home care our mother if we chose to, (actually we had no other choice by then, hey thanks Medicaid!!). But it turned out to be a life-changing, astonishing three years in our family's life: we bonded, worked together and cared for our dear mom who raised us as a single parent for years. It was a time of challenge, humor, loving interaction, good cooking, breaches mended, lively chat, arguments, tears, huge growth, learning, and wonderful memories – enough for a book I am working on. I urge everyone with a beloved family member: read and learn whatever you can about dementias in general, ALZ in particular. Don't give up, keep a perspective and try and smile, even on the bad days. Challenge whatever you feel is wrong – Even Doctors make some really stupid mistakes, trust me..and seek advocacy and support when you feel it is appropriate.
Among other things, I find it damn sad that (almost) everyone that finds themselves in this situation reflexively states, "I'll never put her in a nursing home!" But by doing so they ironically declare war on the very health of their own lives. Without help INSIDE that house, one person can never be asked — or expected — to believe they can take care of another. Because of their stern declaration against skilled nursing care, they always return defeated and ashamed to ask for help. And then that's when other family members who weren't around to help usually pounce and attack the caregiver (spouse)!
Front Pharmacol. 2017 Feb 3;8:20. doi: 10.3389/fphar.2017.00020. ECollection 2017
In Vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease. Watt G1, Karl T2
Alzheimer's disease (AD) is a debilitating neurodegenerative disease that is affecting an increasing number of people. It is characterized by the accumulation of amyloid-β and tau hyperphosphorylation as well as neuroinflammation and oxidative stress. Current AD treatments do not stop or reverse the disease progression, highlighting the need for new, more effective therapeutics. Cannabidiol (CBD) is a non-psychoactive phytocannabinoid that has demonstrated neuroprotective, anti-inflammatory and antioxidant properties in vitro. Thus, it is investigated as a potential multifunctional treatment option for AD. Here, we summarize the current status quo of in vivo effects of CBD in established pharmacological and transgenic animal models for AD.
The studies demonstrate the ability of CBD to reduce reactive gliosis and the neuroinflammatory response as well as to promote neurogenesis. Importantly, CBD also reverses and prevents the development of cognitive deficits in AD rodent models. Interestingly, combination therapies of CBD and Δ9-tetrahydrocannabinol (THC), the main active ingredient of cannabis sativa, show that CBD can antagonize the psychoactive effects associated with THC and possibly mediate greater therapeutic benefits than either phytocannabinoid alone. The studies provide "proof of principle" that CBD and possibly CBD-THC combinations are valid candidates for novel AD therapies. Further investigations should address the long-term potential of CBD and evaluate mechanisms involved in the therapeutic effects described.
"The End of Alzheimer’s is a monumental work. Dr. Bredesen completely recontextualizes this devastating condition away from a mysterious and unsolvable process to one that is both preventable and, yes, reversible. Pinning our hopes on pharmaceutical research to develop a miraculous wonder drug has left both physicians and patients empty handed. But now, this comprehensive approach offers solid results, bringing hope to so many." —David Perlmutter, MD, Board-certified neurologist and author, #1 New York Times bestseller, Grain Brain, and Brain Maker
"The End of Alzheimer's, for the first time, synthesizes the latest science into a practical plan that can reverse Alzheimer's and dramatically improve brain health and function. If you have a brain, read this book." —Mark Hyman, MD, author of the #1 New York Times bestseller Eat Fat, Get Thin
"This book represents a major turning point in our approach to Alzheimer’s disease, from viewing it as a mysterious and incurable affliction that is governed almost exclusively by our genes, to understanding it as a multifactorial condition that can be prevented and even reversed largely through nutrition and lifestyle change. For the first time ever, patients and families affected by Alzheimer’s—as well as those at high risk for this devastating disease—truly have a reason to be hopeful." —Chris Kresser, M.S., L.Ac Founder, Kresser Institute for Functional & Evolutionary Medicine, Author of the New York Times best seller The Paleo Cure
"The End of Alzheimer’s is a masterful, authoritative, and ultimately hopeful patient guide to functional medicine for your brain. It will help you prevent and reverse Alzheimer’s disease, whether you have the ApoE4 gene or not. My patients fear Alzheimer’s more than any other diagnosis. This is the book to transmute fear into action." —Sara Gottfried, MD, New York Times bestselling author of Younger
"Having spent several years implementing many of Dr. Bredesen's insights in my patients, I can assure you that following his advice can save yourself, your loved ones, and your friends from suffering from this preventable and reversible curse." —Steven Gundry, MD, author of the New York Times bestseller The Plant Paradox
"Dr. Dale Bredesen is a world class neuroscientist/neurologist who through his innovative and exacting research has discovered a safe and effective approach to the prevention and treatment of Alzheimer's disease that will revolutionize the way we think about the disease." —Jeffrey Bland, PhD, FACN, FACB; President, Personalized Lifestyle Medicine Institute
"The End of Alzheimer's offers a new beginning in Medicine — changing the focus from a singular disease to recognizing the systems-based approach required to care for the whole person. Dr. Bredesen translates the knowledge of science to the wisdom that helps to heal our people . . . and provide a vision for the end of Alzheimers!" —Patrick Hanaway, MD, Founding Medical Director, Director of Research, Center for Functional Medicine, Cleveland Clinic
"In this engaging, heartfelt, and insightful book, Dr. Bredesen elucidates a bold new approach to Alzheimer's, rooted in decades of his own pioneering research. A must read for anyone wondering what can be done for this dread disease, whether for themselves, a loved one, or a patient." —Nathan Price, PhD, Professor & Associate Director of the Institute for Systems Biology.
this is so tragic. I wish for no one to experience a loved ones slow loss of their ability to remember speak or act themself
Sad 😢
My mom was diagnosed February 2018. By November 2018 she didn't recognize me, thought she lived somewhere else ( her former residence) and reported to Home Health in an Eval. that we were running a prostitution ring, sex trafficking ring with Dog the Bounty Hunter for a $250 registration fee.
I thought this was going to be a collage of 10 yrs. of the patient! 10years of seeing the disease progress, so we can get a better perspective.
Too bad.
Anyone know of a good link that provides this?
At least some risk factors are controllable: diabetes, obesity, high blood pressure, heart disease, head trauma, untreated sleep apnea (hypoxia) & overuse of benzodiazepines & other GABAergics like Ambien all increase your risk for dementia. Some cases are clearly genetic or sporadic but up to 1/3rd of cases could be prevented with healthy lifestyle changes according to studies. The role of high blood sugar/diabetes in dementia cannot be overstated. It damages the small vessels in the brain (microangiopathy), causing leaks that result in all kinds of problems.
For those of us who have dealt with loved ones with this disease, there will not be a toll for many of us, if we ourselves develop it. I, and many others, will take matters into our own hands once it's clear where this is going. This is not a reasonable quality of life.
I just recently left my 14 year career in long term care to start my own business, Reminisce Adult Day Services. I noticed the growing need for respite care for these caregivers. The toll it takes on their health and relationship is saddening. I provide care for their loved one on a regular basis so they can continue to live their lives and take care of their own health. I'm starting small in my local community but would love to expand and help spread this needed service. If you're curious visit http://www.reminisceadultdayservices.com or check us out on FB.
what a nightmare. continual heartbreaks that never let up … and when this woman dies, what is her poor husband supposed to do?
The importance of long-term care insurance cannot be stressed enough. It gives the spouse the ability to bring care into the home (and ultimately find a facility to their liking) and live with some measure of dignity and control in an incredibly difficult situation.
Well, Zaine, I will admit it WAS a major task to do what we did. We were lucky – no one ever dared to 'pounce' on us. One of the reasons: we had no money, (only enough to be refused Medicaid, which has a very low bar if you check the figure for eligibility). But we were praised as variously, "noble, inspired, compassionate, beyond amazing, dutiful, devoted.." on and on. All true. I am 70; my sister is in her late 60's. Mom died at home, in her bed, with us close by. She was 95 and had made her wishes very clear. However, the health care system in this country is a travesty, which caregivers often discover by painful investigation. We sure did!! That said – I would not have traded the experiences we had for anything in the world…but there are many gaps, Scandinavian countries put us to shame in their wonderful eldercare options..but caregivers must often also be warriors. And that, takes time away from the task we must attend to – looking after our beloved mother.We variously locked horns with her old employers, the health insurance company, a nursing home, her union, NYU Neurology, Medicaid, two corrupt eldercare lawyers, on and on…
Years ago, our mother was mis diagnosed, not once but TWICE with AD. What she actually had was mixed senile dementia. And, we then were refused help from Medicaid. That's the bad news. The good news: we had an enlightened Doctor, who suggested that we could home care our mother if we chose to, (actually we had no other choice by then, hey thanks Medicaid!!). But it turned out to be a life-changing, astonishing three years in our family's life: we bonded, worked together and cared for our dear mom who raised us as a single parent for years. It was a time of challenge, humor, loving interaction, good cooking, breaches mended, lively chat, arguments, tears, huge growth, learning, and wonderful memories – enough for a book I am working on. I urge everyone with a beloved family member: read and learn whatever you can about dementias in general, ALZ in particular. Don't give up, keep a perspective and try and smile, even on the bad days. Challenge whatever you feel is wrong – Even Doctors make some really stupid mistakes, trust me..and seek advocacy and support when you feel it is appropriate.
Among other things, I find it damn sad that (almost) everyone that finds themselves in this situation reflexively states, "I'll never put her in a nursing home!" But by doing so they ironically declare war on the very health of their own lives. Without help INSIDE that house, one person can never be asked — or expected — to believe they can take care of another. Because of their stern declaration against skilled nursing care, they always return defeated and ashamed to ask for help. And then that's when other family members who weren't around to help usually pounce and attack the caregiver (spouse)!
https://www.ncbi.nlm.nih.gov/pubmed/28217094
Front Pharmacol. 2017 Feb 3;8:20. doi: 10.3389/fphar.2017.00020. ECollection 2017
In Vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease. Watt G1, Karl T2
Alzheimer's disease (AD) is a debilitating neurodegenerative disease that is affecting an increasing number of people. It is characterized by the accumulation of amyloid-β and tau hyperphosphorylation as well as neuroinflammation and oxidative stress. Current AD treatments do not stop or reverse the disease progression, highlighting the need for new, more effective therapeutics. Cannabidiol (CBD) is a non-psychoactive phytocannabinoid that has demonstrated neuroprotective, anti-inflammatory and antioxidant properties in vitro. Thus, it is investigated as a potential multifunctional treatment option for AD. Here, we summarize the current status quo of in vivo effects of CBD in established pharmacological and transgenic animal models for AD.
The studies demonstrate the ability of CBD to reduce reactive gliosis and the neuroinflammatory response as well as to promote neurogenesis. Importantly, CBD also reverses and prevents the development of cognitive deficits in AD rodent models. Interestingly, combination therapies of CBD and Δ9-tetrahydrocannabinol (THC), the main active ingredient of cannabis sativa, show that CBD can antagonize the psychoactive effects associated with THC and possibly mediate greater therapeutic benefits than either phytocannabinoid alone. The studies provide "proof of principle" that CBD and possibly CBD-THC combinations are valid candidates for novel AD therapies. Further investigations should address the long-term potential of CBD and evaluate mechanisms involved in the therapeutic effects described.
The End of Alzheimer's
https://www.amazon.com/End-Alzheimers-Program-Prevent-Cognitive/dp/0735216207/ref=sr_1_1?ie=UTF8&qid=1508002556&sr=8-1&keywords=the+end+of+alzheimers
"Alzheimer’s is a disease for which there is no cure. Dr. Bredesen’s experimental program gives me hope that there are actions we can all take to care for our brains and keep Alzheimer’s at bay."
—Maria Shriver, Today Show
"The End of Alzheimer’s is a monumental work. Dr. Bredesen completely recontextualizes this devastating condition away from a mysterious and unsolvable process to one that is both preventable and, yes, reversible. Pinning our hopes on pharmaceutical research to develop a miraculous wonder drug has left both physicians and patients empty handed. But now, this comprehensive approach offers solid results, bringing hope to so many."
—David Perlmutter, MD, Board-certified neurologist and author, #1 New York Times bestseller, Grain Brain, and Brain Maker
"The End of Alzheimer's, for the first time, synthesizes the latest science into a practical plan that can reverse Alzheimer's and dramatically improve brain health and function. If you have a brain, read this book."
—Mark Hyman, MD, author of the #1 New York Times bestseller Eat Fat, Get Thin
"This book represents a major turning point in our approach to Alzheimer’s disease, from viewing it as a mysterious and incurable affliction that is governed almost exclusively by our genes, to understanding it as a multifactorial condition that can be prevented and even reversed largely through nutrition and lifestyle change. For the first time ever, patients and families affected by Alzheimer’s—as well as those at high risk for this devastating disease—truly have a reason to be hopeful."
—Chris Kresser, M.S., L.Ac Founder, Kresser Institute for Functional & Evolutionary Medicine, Author of the New York Times best seller The Paleo Cure
"The End of Alzheimer’s is a masterful, authoritative, and ultimately hopeful patient guide to functional medicine for your brain. It will help you prevent and reverse Alzheimer’s disease, whether you have the ApoE4 gene or not. My patients fear Alzheimer’s more than any other diagnosis. This is the book to transmute fear into action."
—Sara Gottfried, MD, New York Times bestselling author of Younger
"Having spent several years implementing many of Dr. Bredesen's insights in my patients, I can assure you that following his advice can save yourself, your loved ones, and your friends from suffering from this preventable and reversible curse."
—Steven Gundry, MD, author of the New York Times bestseller The Plant Paradox
"Dr. Dale Bredesen is a world class neuroscientist/neurologist who through his innovative and exacting research has discovered a safe and effective approach to the prevention and treatment of Alzheimer's disease that will revolutionize the way we think about the disease."
—Jeffrey Bland, PhD, FACN, FACB; President, Personalized Lifestyle Medicine Institute
"The End of Alzheimer's offers a new beginning in Medicine — changing the focus from a singular disease to recognizing the systems-based approach required to care for the whole person. Dr. Bredesen translates the knowledge of science to the wisdom that helps to heal our people . . . and provide a vision for the end of Alzheimers!"
—Patrick Hanaway, MD, Founding Medical Director, Director of Research, Center for Functional Medicine, Cleveland Clinic
"In this engaging, heartfelt, and insightful book, Dr. Bredesen elucidates a bold new approach to Alzheimer's, rooted in decades of his own pioneering research. A must read for anyone wondering what can be done for this dread disease, whether for themselves, a loved one, or a patient."
—Nathan Price, PhD, Professor & Associate Director of the Institute for Systems Biology.
What causes alzimers